From the authors of David Olvera, FP-C and Daniel Davis M.D. The abstract introduction: Rapid sequence intubation (RSI) is associated with a number of complications that can increase morbidity and mortality.  Among RSI agents used to blunt awareness of the procedure and produce amnesia, ketamine is unique in its classification as a dissociative agent rather than a CNS depressant.  Thus, ketamine should have a lower risk of peri-RSI hypotension due to the minimal sympatholysis as compared to other agents.  The main goal of this analysis was to explore the incidence of hypotension and/or cardiopulmonary arrest in patients receiving ketamine versus other agents during RSI.  We hypothesized that ketamine would be associated with a lower risk of hemodynamic complications, particularly after adjusting for co-variables reflecting patient acuity.  In addition, we anticipated that an increased prevalence of ketamine use would be associated with a decreasing incidence of peri-RSI hypotension and/or arrest.  We couldn’t make this podcast without. Please rate, and review wherever you download the podcast. Thanks for listening!

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